Bergen, Norway, August 20, 2024, - BerGenBio ASA (OSE: BGBIO), a clinical-stage
biopharmaceutical company developing novel, selective AXL kinase inhibitors for
severe unmet medical needs, announced today a collaboration with Tempus, a
technology company leading the adoption of AI to advance precision medicine and
patient care, to advance the clinical development of BerGenBio's selective AXL
inhibitor bemcentinib in first line (1L) Non-Small Cell Lung Cancer (NSCLC)
patients with STK11 mutations (STK11m). BerGenBio's on-going BGBC016 Phase 1b/2a
trial is designed to assess the benefit of adding bemcentinib to the current
standard of care treatment (immunotherapy + doublet chemotherapy) in 1L STK11m
patients, a population with poor outcomes and no specific therapies today.
The collaboration will provide BerGenBio with access to a tailored cohort of
Tempus' real-world clinical and molecular data that is intended to establish a
synthetic control to provide a contextual benchmark for BerGenBio's innovative
study, which aims to address the urgent medical need for effective treatments in
STK11m NSCLC patients. Tempus' comprehensive, AI-enabled platform will enable
BerGenBio to receive customized analyses of Tempus data and gain deeper insights
into the genomic landscape and therapeutic responses of NSCLC patients with
STK11m.
Upon conclusion of the BGBC016 study, the parties intend to present insights
derived from the resulting data to appropriate regulatory agencies as a next
step in the further development of bemcentinib.
Martin Olin, CEO of BerGenBio, expressed enthusiasm about the collaboration,
stating, "We are excited to partner with Tempus to harness the power of their
advanced technology in our mission to improve outcomes for NSCLC patients with
STK11 mutations. By integrating Tempus' platform into our study, we aim to
enhance our understanding of the disease biology and treatment outcomes,
ultimately driving our ability to accelerate further development of
bemcentinib".
"We are excited to collaborate with BerGenBio to accelerate the development of
precision therapies for STK11m NSCLC patients," said Kate Sasser, Chief
Scientific Officer at Tempus. Together, we aim to unlock new insights that will
ultimately improve patient outcomes and redefine the standard of care in this
challenging disease setting."
For further information, please contact:
Contacts
Martin Olin CEO, BerGenBio ASA
ir@bergenbio.com
Rune Skeie, CFO, BerGenBio ASA
rune.skeie@bergenbio.com
Investor Relations / Media Relations
Jan Lilleby
jl@lillebyfrisch.no
About BerGenBio ASA
BerGenBio is a clinical-stage biopharmaceutical company focused on developing
transformative drugs targeting AXL as a potential cornerstone of therapy for
aggressive diseases, including cancer and severe respiratory infections. The
Company is focused on its proprietary lead candidate, bemcentinib, a potentially
first-in-class selective AXL inhibitor in development for STK11 mutated NSCLC
and severe respiratory infections. BerGenBio is based in Bergen, Norway with a
subsidiary in Oxford, UK. The company is listed on the Oslo Stock Exchange
(ticker: BGBIO). For more information, visit www.bergenbio.com
This information is subject to the disclosure requirements pursuant to section 5
-12 of the Norwegian Securities Trading Act.