contentSlug

type

ContentSlug_ContentQuery

slug

ContentPageContentQuery

content

trendingContent

query ContentSlug_ContentQuery(
  $contentSlug: String!
  $type: [ContentType!]
) {
  ...ContentPageContentQuery_13QmVO
}

fragment CompanyDetails_Content on Content {
  __isContent: __typename
  companies {
    name
    description
    pageUrl
    id
  }
}

fragment CompanyTagList on Company {
  pageUrl
  name
  viewerIsFollowing
}

fragment ContentBasicInfo on Content {
  __isContent: __typename
  id
  type
  title
  lang
  companies {
    ...CompanyTagList
    id
  }
  ...PublishingDetails
  ...Reactions
}

fragment ContentMetadata on Content {
  __isContent: __typename
  type
  title
  lang
  pageUrl
  alternatePageUrls: translations {
    __typename
    pageUrl
    lang
  }
  imgUrl
  description
  ... on Video {
    liveTime
    videoUrl
  }
  ... on Webcast {
    liveTime
    videoUrl
  }
}

fragment ContentPageContentQuery_13QmVO on Query {
  content(slug: $contentSlug, type: $type) {
    __typename
    id
    type
    title
    isPremium
    lang
    htmlBody
    companies {
      forum {
        latestPosts {
          ...ForumPosts
        }
      }
      defaultInstrument {
        isin
        id
      }
      id
    }
    slug
    ... on CompanyReport {
      reportUrl
    }
    ... on ThirdPartyCompanyReport {
      reportUrl
    }
    ... on StockExchangeRelease {
      reportUrl
    }
    ...ContentBasicInfo
    ...ContentMetadata
    ...PriceAndRecommendation_Content
    ...CompanyDetails_Content
    ...ReportLink_Content
    ...KeyFigures_Content
  }
  ...TrendingContent_1jQ2Cn
}

fragment ForumPosts on ForumPost {
  text
  likesCount
  url
  author
  postedAt
  authorImgUrl
}

fragment KeyFigures_Content on Content {
  __isContent: __typename
  companies {
    defaultInstrument {
      estimateData {
        modelType
        reportingCurrency
      }
      snapshot {
        transaction {
          date
          actualized {
            year
            quarter
            revenue
            revenueGrowth
            ebitAdjusted
            ebitReported
            ebitda
            enterpriseValue
            epsAdjusted
            dividend
            dividendYield
            sharePrice
          }
          estimates {
            year
            quarter
            revenue
            revenueGrowth
            ebitAdjusted
            ebitReported
            ebitda
            enterpriseValue
            epsAdjusted
            dividend
            dividendYield
            sharePrice
          }
        }
      }
      id
    }
    id
  }
}

fragment PriceAndRecommendation_Content on Content {
  __isContent: __typename
  createdAt
  companies {
    id
    name
    viewerIsFollowing
    defaultInstrument {
      snapshot {
        priceData {
          date
          lastPrice
          tradeCurrency
        }
        transaction {
          date
          recommendation
          targetPrice
        }
        prevTransaction {
          recommendation
        }
      }
      id
    }
  }
}

fragment PublishingDetails on Content {
  __isContent: __typename
  createdAt
  publishers {
    name
    imgUrl
  }
  authors {
    __typename
    id
    name
    slug
    imgUrl
    jobTitle
  }
  ... on Video {
    liveTime
  }
  ... on Webcast {
    liveTime
  }
}

fragment Reactions on Content {
  __isContent: __typename
  id
  reactionGroups {
    reactionType
    reactionsCount
    viewerReacted
  }
}

fragment ReportLink_Content on Content {
  __isContent: __typename
  type
  isPremium
  ... on CompanyReport {
    reportUrl
  }
  ... on ThirdPartyCompanyReport {
    reportUrl
  }
  ... on StockExchangeRelease {
    reportUrl
  }
}

fragment TrendingContent_1jQ2Cn on Query {
  trendingContent(type: ARTICLE) {
    __typename
    id
    title
    lang
    pageUrl
    createdAt
    type
    imgUrl
    companies {
      squareLogoUrl
      id
    }
    authors {
      __typename
      imgUrl
      id
    }
    publishers {
      imgUrl
    }
  }
}


biosergen-ab-biosergen-announces-safety-committee-approval-to-proceed-with-dose-escalation-in-second-cohort-for-bsg005-clinical-trial

__typename

title

isPremium

lang

htmlBody

companies

createdAt

publishers

authors

reactionGroups

pageUrl

translations

imgUrl

description

Biosergen is a biotechnology company. The company specializes in the research and development of various pharmaceuticals. The product portfolio includes, for example, the company's product BSG005, a fungicidal pharmaceutical in the clinical phase. In addition to the main business, service and associated ancillary services are also offered. The company operates in Norway. Biosergen was founded in 2004 and is headquartered in Solna.

Biosergen

November 7, 2024 - Biosergen AB ("Biosergen"), a clinical-stage biotechnology company developing therapies for life-threatening fungal infections, today announced that an independent Safety ...

<div class="abstract"><p>November 7, 2024 - Biosergen AB ("Biosergen"), a clinical-stage biotechnology company developing therapies for life-threatening fungal infections, today announced that an independent Safety Review Committee has approved the continuation of dose escalation in its ongoing proof-of-concept trial for BSG005. Following a favorable review of safety data from the first cohort, a new cohort of five patients will soon begin treatment at an increased dose level.</p></div><p>"We are encouraged by the Safety Review Committee's positive review of BSG005's safety profile in the initial cohort, and we look forward to evaluating the effects of dose escalation in the next group of patients," said Tine Olesen, CEO of Biosergen. "This decision marks an important step in our clinical program, and we are pleased to continue our proof-of-concept trial as planned, remaining on track to enroll and treat three cohorts by January 2025."</p><p>The current proof-of-concept trial assesses BSG005's safety, tolerability, and efficacy as a rescue therapy for patients with potentially life-threatening fungal infections who have limited or no treatment options. The initial cohort, treated at a lower dose, demonstrated promising outcomes with no significant safety concerns reported. This led to longer treatments and higher doses than first anticipated, underscoring the clinical investigators' emerging confidence in BSG005's safety and promising efficacy even at this early stage. Based on this data, the committee has approved the initiation of the second cohort.</p><p>In the first cohort, the daily dose was gradually escalated from 0.1 mg/kg to a maximum of 0.8-1 mg/kg, as, in two cases, patients felt well enough to independently opt to leave the hospital before reaching 1 mg/kg. For the second cohort, it is planned to escalate the dosing from 0.8 mg/kg to 1.5mg/kg, dependent on safety and efficacy data of the individual patient.</p>

Biosergen AB: Biosergen Announces Safety Committee Approval to Proceed with Dose Escalation in Second Cohort for BSG005 Clinical Trial